Under physio-pathological conditions, cells release membrane-surrounded structures named Extracellular Vesicles (EVs), which convey their molecular cargo to neighboring or distant cells influencing their metabolism.Besides their involvement in the intercellular communication, EVs might represent a tool used by cells to eliminate unnecessary/toxic m
Abstract The cellular organization of gastrointestinal crypts is orchestrated by different cells of the stromal niche but Belts available in vitro models fail to fully recapitulate the interplay between epithelium and stroma.Here, we establish a colon assembloid system comprising the epithelium and diverse stromal cell subtypes.These assembloids re
Abstract Background Mast Cell Activation Syndrome (MCAS) is classified as an idiopathic mast cell disorder where inconsistent or unknown triggers release inflammatory mediators and cause a constellation of symptoms.Studies demonstrate mast cells increase histamine, tryptase, and inflammatory cytokine expression following ionizing radiation.Addition
Artistic images of animal characters in beast stories studied through the prism of national mentality reveal specific animal-human concepts rooted in the readers’ mindsets.This essay focuses on the hare/rabbit as a popular character in animal tales, with an attempt to enhance intercultural relations in the Ukrainian/English world by explaining th
Prostate cancer is the third most common cancer in men globally, and the most common cancer among men in the United States.Dietary DJ Systems choices may play an important role in developing prostate cancer; in particular, a higher dairy product intake has been associated with an increased risk of developing prostate cancer.The overall positive ass